Intravenous iron requirement in adult hemodialysis patients
نویسندگان
چکیده
منابع مشابه
Ferumoxytol as an intravenous iron replacement therapy in hemodialysis patients.
BACKGROUND AND OBJECTIVES Intravenous iron is a key component of anemia management for chronic kidney disease (CKD). Ferumoxytol is a unique intravenous iron product that can be administered as a rapid injection in doses up to 510 mg. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This was a randomized, open-label, controlled, multicenter Phase 3 trial to evaluate the safety and efficacy of in...
متن کاملAngina pectoris and intensive intravenous iron treatment in hemodialysis patients.
BACKGROUND Intravenous iron and erythropoietin are commonly used for the treatment of anemia in end stage renal disease (ESRD) patients. Even though i.v. iron is proven to be very effective, there is great concern regarding its possible toxic effects. The aim of our study was to evaluate the possible correlation between iron administration and the incidence of angina pectoris in hemodialysis pa...
متن کاملIntravenous iron exposure and outcomes in patients on hemodialysis.
Iron is an essential trace element that is important for normal body function. However, excess iron in animal studies has been shown to be toxic, because it can enhance radical oxygen generation, impair neutrophil and T-cell function, and also promote bacterial growth (1,2). This dichotomy requires the body to meticulously regulate iron homeostasis, perhaps more than any other substance. Iron c...
متن کاملIntravenous iron exacerbates oxidative DNA damage in peripheral blood lymphocytes in chronic hemodialysis patients.
Patients undergoing maintenance hemodialysis have elevated markers of oxidative stress, but the reasons for this are not fully understood. Intravenous administration of iron, which many of these patients receive, may provoke the generation of bioactive iron, which enhances oxidative stress and lipid peroxidation. In this study, 110 hemodialysis patients were randomly assigned to five groups tha...
متن کاملIntravenous Iron Supplementation Practices and Short-Term Risk of Cardiovascular Events in Hemodialysis Patients
BACKGROUND & OBJECTIVES Intravenous iron supplementation is widespread in the hemodialysis population, but there is uncertainty about the safest dosing strategy. We compared the safety of different intravenous iron dosing practices on the risk of adverse cardiovascular outcomes in a large population of hemodialysis patients. DESIGN SETTINGS PARTICIPANTS & MEASUREMENTS A retrospective cohort w...
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ژورنال
عنوان ژورنال: Dialysis & Transplantation
سال: 2006
ISSN: 0090-2934,1554-8309
DOI: 10.1002/dat.20047